ReShape Lifesciences Inc. (NASDAQ:RSLS), a developer of minimally invasive medical devices to treat obesity and metabolic diseases, announced today that the Company will be presenting early results of a new, novel use of the ReShape Lifesciences™ neuro-blocking technology in combination with separate-site vagus nerve stimulation for the treatment of type 2 diabetes. Results of a recent study, which examines this first-ever application for the treatment of type 2 diabetes, will be discussed in a poster presentation during the Minnesota Neuromodulation Symposium taking place at the Graduate Minneapolis Hotel from April 12-13, 2018.
The poster will discuss the use of the ReShape Lifesciences neuro-blocking technology in combination with pacing stimulation of the pancreas as a method to lower plasma glucose in a rat model of type 2 diabetes.
In the study, a proprietary bio-electronic device and algorithm developed by ReShape Lifesciences was used to study for the first time ever the effect of multi-site electrical neuromodulation via the vagus nerve. The study involved the simultaneous nerve pacing and neuro-blocking of two branches of the vagus nerve, innervating the pancreas and the liver, respectively, followed by continuous measurement of plasma glucose. Results showed that glycemic control was significantly increased following an elevated glucose challenge in the ReShape Lifesciences neuromodulation rats compared to those in the control.
ReShape Lifesciences currently has two patents on this methodology and one pending application.
Type 2 diabetes mellitus presents one of the largest unmet needs in healthcare. Twenty-nine million Americans currently suffer from type 2 diabetes and an additional 84.1 million pre-diabetics risk becoming diabetic.
Presentation Details:
Friday, April 13, 2018, 10:45 AM - 1:30 PM CT, Pinnacle Ballroom
Presentation Title:
"Simultaneous Multi-Site Vagus Nerve Neuromodulation with ReShape's Bio-electronic Device Improves Glycemic Control in an Obese Rat Model of Type 2 Diabetes Mellitus"
Presenters:
Dr. Jon Waataja, Director of Research, ReShape Lifesciences and Dr. Raj Nihalani, Chief Technology Officer, ReShape Lifesciences
For more details on the Minnesota Neuromodulation Symposiums, please visit http://neuromodulation.umn.edu/.
About ReShape Lifesciences Inc.
ReShape Lifesciences™ is a medical device company focused on technologies to treat obesity and metabolic diseases. The FDA-approved ReShape Balloon™ System involves a non-surgical weight loss procedure that uses advanced balloon technology designed to take up room in the stomach to help people with a 30-40 kg/m2 Body Mass Index (BMI) and at least one co-morbidity lose weight. ReShape vBloc™ Therapy, delivered by an FDA-approved pacemaker-like device called the ReShape vBloc System, is designed to help patients with a 40-45 kg/m2, or a 35-39.9 kg/m2 BMI and at least one co-morbidity feel full and eat less by intermittently blocking hunger signals on the vagus nerve. The ReShape Vest™ System is an investigational, minimally invasive, laparoscopically implanted medical device that wraps around the stomach, emulating the gastric volume reduction effect of conventional weight-loss surgery, and is intended to enable rapid weight loss in obese and morbidly obese patients without permanently changing patient anatomy.
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