News
Products
Suppliers
News
Search
All Categories
Products or Suppliers
Content Hub
Product Zone
Sponsorship & Membership
CPHI & PMEC China
Correctives Colorant Filtration separation Intelligent Logistics Cold chain Technical &Materials Logistics Equipment &Materials Storage Equipment &Materials Logistic Services Third-party logistics Dangerous Goods Logistics Level instrument Pressure gauge Thermometers Flow meter Gas analysis instrument Liquid analysis instrument Fermenter Equipment Other Measuring Instrument Other Logistics Medical Aesthetic Consumables Sera and Vaccines Soft tube/Hard tube Pharmaceutical Intermediates Anti-tumor Preparations Pharmaceutical Manufacturing Outsourcing Chemical and Biochemical Reactors Mixing Equipment CIP System(Clean in place) Herbal medicine Concentration Equipment Purification Equipment Low Temperature Refrigeration Seals Laboratory General Equipment Functional Food Raw Materials Inner packaging equipment Polluted Water / Wastewater Treatment Equipment Injection Raw Materials and Ingredients IVD (In Vitro Diagnostics) Consumables Suspending Agents / Thickening Agents Concentrator Equipment MES System APIs for Anti-Infective Drugs Biochemical APIs Botanical products Pharma Packaging Materials Diluents (Fillers) Intermediates for Agrochemicals Reagent Cardiovascular, Cerebrovascular, and Circulatory System Formulations Pharmaceutical R&D Outsourcing Drying Equipment TCM Pulverizer Water Purification Equipment Purification Test Instrument Air Conditioner ‌Sanitary Fittings Analytical Instrument Other Dipstick Consumables Nutraceutical Ingredients Granules Machinery Outer packaging Waste Gas Treatment Equipment Active Ingredients Binders Solubilizers Drug delivery systems Sensors APIs for Nervous System Drugs Animal-derived products Endocrine and Metabolic Preparations Disintegrants service Crystalling Equipment Pill Making Equipment Other Water Treatment Equipment Clean Clothes/Clean Cap/Clean Shoes Cold Storage Pumps Food & Beverage Raw Materials Life Science Instrument Tablet equipment Other pharmaceutical packaging equipment Solid and Hazardous Waste Treatment Equipment Innovative Materials Controllers & Drivers Speciality Intermediates Microbial products Humectants APIs for Digestive System Drugs APIs for Cardiovascular System Drugs Antibacterial and Antiviral Formulations Lubricants Extraction Plant Slice Machine Clean Bench ‌Refrigeration Auxiliaries Valves Biologics TCM Raw Materials Food Additive Reagents and Consumables Capsule equipment Pharmaceutical water equipment Testing & Monitoring Instruments and Equipment Other Medical Aesthetics & Skincare Veterinary Pharmaceutical Intermediates Automation Software APIs for Respiratory System Drugs Bio Technology Service Antipyretic and Analgesic Preparations Glidants / Anti-caking Agents Heat Exchanger Herbal medicine Drying Equipment Air Shower Room Compressor Cylinders Fine Chemicals Crushing equipment Ultrapure Water System Other Automation & Informatization Products OEM/ODM Measuring Instruments Energy-saving and Low-carbon Equipment Other Intermediates Antiparasitic Preparations Coating Agents Storage Tanks, Containers Herbal medicine Extraction Equipment Air Purification Other Refrigeration Equipment Drive Equipment‌ Liquid preparation equipment Solution Preparation System Other Environmental Protection Equipment APIs for Hormones and Regulatory Drugs Other Natural Products Physical Testing APIs for Antiparasitic Drugs Anti-Allergic Formulations Plasticizer Evaporating Equipment TCM Cooking Equipments Cleanroom Reducers Laboratory Engineering Biopharmaceutical Equipment Membrane Module‌ APIs for Antipyretic and Analgesic Drugs Anti-Tuberculosis and Anti-Leprosy Formulations Surfactant Distillation Equipment Drop Pill Equipment Purifying Engineering VFD (Variable Frequency Drive) Other preparation equipment Distilled water machine Laboratory Solutions Vitamin Digestive System Preparations Centrifuge Screening Machine Honey Pill Machine Flooring Materials Bearing Emulsifiers Ion-exchange equipment Online Process Control Respiratory System Preparations Sterilizing Equipment TCM Deposition Equipment Spare Part‌ Other Cleaning System Stainless Steel Nervous System Preparations Filter press equipment Herbal medicine Fermentation Equipment Plastic ‌Containment System Special Active Ingredients Ointment Bases Homogenizer Equipment Other TCM Machinery Others Parts and Components APIs for Veterinary Drugs and Feed Additives Anaesthetic and Adjuvant Formulations Air Filter Suppository Bases Other Active Pharmaceutical Ingredients Blood System Formulations Cleanroom Consumables‌ Glass lining equipment Film-forming Agents Urinary and Reproductive System Formulations Other API Machinery and Equipment Filter Paper Release Modifiers Immunomodulatory Formulations Filter Paper Board smotic Pressure Regulators / Tonicity Adjusting Agents Water, Electrolyte, and Acid-Base Balance Regulating Formulations Ph Control Agents Nozzle, Tank Cleaning Machine Vitamin, Mineral, and Amino Acid Formulations Antioxidants / Antioxidant Synergists Fluid Equipment Enzyme and Other Biochemical Formulations Antimicrobial Preservatives (Preservatives) Tonic and Nutritional Formulations Complexing Agents (Chelating Agents / Inclusion Compounds) Hormonal Formulations Dermatological Preparations Other Preparations Co-solvents ENT Preparations Penetration Enhancers (Transdermal) Freeze-drying Protective Agents Refrigerants / Cryogens Capsule Fragrances Adsorbents Pressure-sensitive Adhesives (PSA) Stiffening Agents Carriers for Dry Powder Inhalers (DPI Carriers) Other Excipients
Pipes and Pipe Fittings Vacuum Equipment Air Compressor Compressor Other Fluid Equipment Prefillable Syringes Filters Filter Presstem Filtration System Filter Bag Filter Mesh Filter Cloth Filter Membrane Other Filtration Equipment Sanitary Pressure Vessel‌ Hyaluronic Acid Collagen Botulinum Toxin Peptide Other Injection Raw Materials and Ingredients Ceramide Ectoin Niacinamide Asiaticoside Ergothioneine Chitosan Other Active Ingredients Chiral Intermediates Advanced Intermediates Microfiltration Ultrafiltration Auxiliary Equipment Separation equipment Metered Dose Inhalers Dry Powder Inhalers Penicillin Hormones Central Nervous System Drugs Reagents for Biopharmaceuticals Drug Target Discovery and Validation Plant Extracts Animal Extracts Synthesis/Screening Process Development/Optimisation/Scale-Up Production Drug Registration and Submission Services Ointment Filling-sealing Machine、Vacuum Mixer Eye Drug Machinery Soft Gelatin Capsule Machinery Tablet Press Pneumatic Cracker Granulator Labelers, Label Printers Bag Packaging Machine Thermostatic / Heating / Drying Equipment Chromatography Particle Size / Particle / Powder Analysis Instruments Tabletop Glass bottles & Vials Fermentation Products Prophylactic Biological Products Mixing Tank/Blender Bioreactor Intravenous Infusion Set Assembly Equipment(Pen Assembly Equipment) PCR Recombinant Collagen Alkaloids Veterinary API Regulated Fine Chemicals Peptides Balances / Weighing Scales Online Gas Chromatography Cephalosporins Anesthetics Immunology Reagents Drug Development Technologies Pharmaceutical Chemistry Formulation Design Regulatory and Compliance Consulting Syrup Machinery Injection Medicine Machinery Hard Capsule Filling Machine Coating Machine Medicine Material Grinding Machine Lettering machine Box Packaging Machine Mass Spectrometry Laboratory Bench Aluminum Foil Rheometers / Viscometers ‌Chemical Reagents Cleaning & Disinfection Equipment Granulator Emulsifier Biological Fermentation System Injection Molding Equipment Exosome Phospholipids Prostaglandins Veterinary Biologics Chemical Reagents Therapeutic Biological Products Biochemical Reagents Antibodies Natural Pigments Animal Lipids Enzyme Preparations Flowmeters Online Particle Size Analyzer Tetracycline Amino Acids and Derivatives Process Optimization and Testing Nucleic Acids and Derivatives Pre-Clinical Research Chemical/Biological API Manufacturing Powder Filling Machine Oral Liquid Machinery Low Temperature Pulverizer Strapping machine Paper Film Packaging Machine Thermal Analyzers Spectrometers Other Measurement and Metrology Instruments Storage Cabinets Plastic Bottles Other Industrial Process Control and Online Analytical Instruments Certification Feed Additives Diagnostic Biological Products Pulverizer Coating Machine Capsule Filling Machine Other Mixing Equipment Cell Engineering Equipment Pre-filled Syringe Production Equipment Purification Equipment Electrophoresis/Gel Imaging/UV Detection Regenerative Materials Other Fine Chemicals Cell Biology Reagents Biological Consumables Feed Additives Soft Mist Inhaler Plant Polysaccharides Animal Proteins Microbial Polysaccharides Aminoglycoside Enzymes Molecular Biology Reagents Clinical Trials Intermediate Synthesis and Production Market and Business Strategy Consulting Suppository Drug Machinery Powder Injection Machinery Pharmaceutical Milling Machinery Printing Device Blister Packaging Machine Environmental Test Chambers Moisture Analyzer Air Discharge Equipment Rubber Stopper Tablet Press Other Tablet Equipment Capsule Production Line Isolator Synthesis/Reaction Equipment Microbial Detection Instrument Composite Biomaterials Animal Breeding Auxiliary Products Packaging Testing Equipment Laboratory Glassware and General Consumables Preclinical Research Services Nebulizer Essential Oils Animal Polysaccharides Bioactive Functional Ingredients Macrolides Microbial / Fermentation Reagents Proteins Other Technology Services Biotechnology Services Formulation Development and Manufacturing Other Services Medicine Film Drug Machinery Infusion Medicine Machinery(中文站有输液剂机械的三级分类) Pharmaceutical Machine Milling Instruction Booklet Folding Machine Fan Chromatography Consumables and Accessories Other Physical Properties Testing Instruments Gasket Sample Preparation / Digestion Equipment X-ray Structure Analysis Safety Cabinet Counting Machine (Tablet) Other Capsule Filling Equipment Disposable Biotechnology Equipment Vacuum Packaging Machine Laboratory Low-temperature Storage Other Innovative Materials Other Veterinary Conveying equipment Natural Spices Bile Acids and Active Ingredients Sulfonamides Other Specialized Reagents Computational Chemistry and AI-Assisted Drug Design Clinical Trial Drug Manufacturing Aerosol Drug Machinery Super Micro Mill Bottle Conveyer Bundling Packaging Machine Mixing/Dispersion Equipment Other Laboratory Complete & Ancillary Equipment Trays Other Laboratory Consumable Other Preparation Machinery for Solid Medcine ‌Centrifugal Separation System Automatic Packaging Machine Other Analytical Instrument Chip System/Accessories Cytokines Counting Machine Cartridge Vial Medicinal Herbs Bee Products Chloramphenicols Testing Other Pharmaceutical Manufacturing Outsourcing Medicine Filling Machine Disk Type Bottle Straightening Machine Lidding Materials Other Crushing Equipment Ultrafiltration/Microfiltration System Horizontal Pillow Packaging Machine Cartoning Machine Auto-injector Transfection/Cell Fusion Track & Trace Gas Generators / Gas Handling Equipment Blood Products TCM Ingredients & Slices Animal Medicinal Materials Lincomycin Microbial Products Bottle Washer Vial Sealing Machine Liquid Handling Equipment Hoses and Fittings Other Biopharmaceutical Equipment Vertical Packaging Machine Casing Machine Microplate Reader/Enzyme Labeling Instrument Analysis and Validation Serialization System Pen Injector Other Anti-Infective Drug Other Pharmaceutical R&D Outsourcing Conveyer For Medicine Material Spray Pump Other Injectable Equipment Aluminum Foil Packaging Machine Coding Machine Cell Analysis Automated Assembly Other Laboratory General Equipment Packaging Bag Valve Freeze Dryer Granule packaging machine Other Drug Delivery Device Accessories Biological Microscope/In Vivo Imaging Other Antibiotics Cap Screwing Machine Nasal Drug Delivery Devices / Nasal Spray Pumps Printing Services‌ Liquid Packaging Machine Laboratory Automation Screw Capping Machine Lamp Inspection Machine Ophthalmic Drug Delivery Devices / Eye Drop Delivery Systems Labelling Powder Packaging Machine Synthesizer Heat Shrink Packaging Machine Metal Detector Insulin Pens / Blood Glucose Management Devices Security Taggants & Markings Filter Cartridge‌ Tablet Packaging Machine Animal Experiment Instrument Injection & blow molding machines Batching system Self-Injection Systems / Safety Protection Devices Incubator Equipment Printed Drugs Packaging Box filling & sealing machine Palletizing equipment CIP cleaning system Topical / Gynecological / Intimate Drug Delivery Devices Desiccants Other Life Science Instrument Bottle Filling Line Contaners Lifting Charging Machine Others Inhalant Packaging BFS Bottlepack Machine Weighting Equipment Blister Packaging Machine Pharmaceutical Paper Other Pharmaceutical Outer Packaging Equipment Packaging bag valve Container Sealing Machine Glass Tube Multi-functional Bottle Packaging Machine Medical Aesthetic Freeze-Dried Powder Vials Sachets Cartoner Packing line Primary Packaging Other Pharmaceutical Inner Packaging Equipment Aluminum Caps & Aluminum-Plastic Combination Caps Sterile Bags / Breathing Bags / Sterilization Bags Medical Device Packaging / Bioconsumables Packaging Dispensing Bottles Blister Packaging Pharmaceutical Plastic Films / Composite Film Bags Accessories Ampuls Other Packaging Materials
Home Industry Insights Pharma Experts Muhammad Asim Niazi
Types of packaging integrity testers
Muhammad Asim Niazi

Freelance Technical Engineering Writer

Types of packaging integrity testers

by Muhammad Asim Niazi

March 3, 2023

Introduction

There are various types of packaging integrity testers for checking the integrity of the packaging. The selection of different types depends on the product and packaging being used. Each type has a separate application and cannot be interchanged from other types.

For optimum and reliable results, it is necessary for the concerned personnel and operators to know various types of packaging integrity testers. Otherwise, it will result in the wrong selection of integrity tester and affect the integrity of the packaging.

How do select different integrity testing methods

As discussed above, there are different types of packaging integrity testers. For accurate results, it is necessary to study the requirements and select the packaging integrity tester. 

Below are some criteria that can help select the correct packaging integrity tester.

Inline vs. Offline

Inline integrity testers check the integrity of packaging during production without taking the sample away from the machine in the laboratory or test bench. The test is performed in the running condition of the machine without stopping or halting the production process. Inline testers are integrated with the production machine. The production machine's main controller continuously monitors these testers' output. A mechanical assembly separates the defective packaging from the correct packaging by taking command from the main controller of the machine.

Offline testers check the packaging integrity away from the machine. The machine is stopped from taking samples until results are obtained. The test is often performed in the laboratory or on a separate test bench. When the trial is concluded, the result is communicated to the concerned personnel for further processing. 

Primary Packaging Type

The packaging material that comes in direct contact with the product is called primary packaging material. Integrity testing for each primary packaging is different and follows a different technique and methodology. For example, the integrity tester for a blister pack cannot be the same as that of ampoules.

Filled Container or empty Container

Integrity tester also depends on whether the Container being tested is empty or contains a product. Some test methods are not suitable for empty containers, as they damage the Container and cannot be used for the product. Similarly, some test methods are not suitable for filled containers, as it affects the test output.

Product Type

Packaging integrity testing also depends on the product being used in packaging material. Different test techniques behave differently on different products. Packaging integrity testing can output inconsistent results if the appropriate product type is not correctly selected. 

In some cases, a particular test method is not suitable for liquid products, while others are not suitable for the solid dosage form. They produce unreliable and erratic results when the appropriate product type is not considered.

Destructive Vs. Non-destructive test 

Packaging integrity testers can be divided into destructive and non-destructive. They are classified according to the usability of the packaging after performing integrity testing.

Destructive Testing

Destructive testing refers to the destruction of packaging, and the product inside it requires re-packing before marketing or reaching its intended user. The product remains safe and can be used for consumption by its end user. 

In Destructive testing, the test mechanism penetrates the packaging material or is performed by immersing the packaging into the sole liquid. This method destroys the packaging, and the product is exposed. The product requires re-packing before it reaches its intended user.

Non - Destructive Testing

In non - destructive testing, the packaging is not dest...

Read More
Subscribe

Get alerted on the PharmaSources E-Newsletter and Pharma Sources Insight E-Compilation!

Subscribe

Note: You can unsubscribe from the alerts at any time.

Subscribe

Get alerted on the PharmaSources E-Newsletter and Pharma Sources Insight E-Compilation!

Subscribe

Note: You can unsubscribe from the alerts at any time.

Pharma Sources Insight
Pharma Sources Insight July 2025: GLOBAL APISOURCING TRENDS
READ ONLINE
DOWNLOAD
Pharma Sources Insight January 2025: What are Reshaping Pharma's Future?
READ ONLINE
DOWNLOAD
Pharma Sources Insight June 2024: Globalization on the Go
READ ONLINE
DOWNLOAD
Pharmaceutical Industry in 2024: Flexible Production, Innovative Drugs and Personalized Medicine
READ ONLINE
DOWNLOAD
PSI April 2023: Innovative Drugs Going Aroad
READ ONLINE
DOWNLOAD
PSI June 2022: New Developments, Greater Imapct
READ ONLINE
DOWNLOAD
PSI APRIL 2022: A Universal Vaccine Against All Variants
READ ONLINE
DOWNLOAD
PSI January 2021: Rolling Out the Vaccines
READ ONLINE
DOWNLOAD
PSI August 2020: The Great Journey or Recovery
READ ONLINE
DOWNLOAD
PSI December 2021: Quantum Revolution in Drug Discovery
READ ONLINE
DOWNLOAD
PSI August 2021: New Medtechs Shaping the Industry
READ ONLINE
DOWNLOAD
PSI April 2021: The Future of Immunotherapy
READ ONLINE
DOWNLOAD
PSI October 2020: Pharma Landscape in China
READ ONLINE
DOWNLOAD
PSI June 2020: A Post-pandemic Future
READ ONLINE
DOWNLOAD