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Overview
1-(2-Chloro-4-nitrophenyl)piperazine (CAS: 16087-95-5) is a key organic intermediate defined by its nitro-chlorophenyl piperazine structure. Synthesized via nucleophilic substitution of chloronitrobenzene with piperazine, it serves as a critical scaffold for pharmaceutical synthesis. Molecular formula: C10H12ClN3O2.
Application
- Pharmaceutical intermediates for antipsychotic and antidepressant drug development.
- Synthesis of complex heterocyclic compounds in agrochemical research.
- R&D precursor for novel kinase inhibitors in oncology studies.
Precautions
Store in a cool, dry, well-ventilated area away from oxidizers. Use appropriate PPE to avoid skin contact and inhalation of dust. Not intended for direct clinical use; strictly regulated as an industrial chemical intermediate.