Soluble in hot ethanol, chloroform, ether, carbon disulfide and glacial acetic acid, slightly soluble in cold ethanol, insoluble in water. Toxic, median lethal dose (mouse, oral)390mg/kg. It's stimulating.
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Overview
1-Chloro-3-nitrobenzene (CAS: 99-08-1) is a key aromatic intermediate with formula C6H4ClNO2. It is primarily produced via nitration of chlorobenzene using mixed acid processes under controlled temperature conditions.
Application
- Synthesis of pharmaceutical intermediates including antihistamines and analgesics.
- Production of agrochemicals such as herbicides and fungicides.
- Manufacturing of dyes, pigments, and optical brighteners.
Precautions
Store in cool, dry, ventilated areas away from incompatible oxidizers. Use appropriate PPE to prevent skin contact and inhalation; avoid release into the environment due to potential toxicity.