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Overview
1,8-Dichloroisoquinoline (CAS 2096-45-7) is a key heterocyclic intermediate with molecular formula C9H5Cl2N. It is primarily synthesized via chlorination of isoquinoline derivatives or condensation reactions. This compound serves as a critical building block for constructing complex nitrogen-containing scaffolds in pharmaceutical manufacturing.
Application
- Synthesis of antiviral agents targeting RNA polymerases.
- Production of kinase inhibitors for oncology research.
- Development of agrochemical fungicides and herbicides.
Precautions
Store in a cool, dry, well-ventilated area away from oxidizers. Use appropriate PPE including gloves and eye protection to prevent skin irritation. Avoid inhalation of dust; do not use in clinical settings without rigorous purification validation.