Category:
Chiral Intermediates
CAS NO:
147027-10-9
Standard:
In-house Standards,
/
(1R,2S,5R)-menthyl 5S-(cytosine-1-yl)-[1,3]-oxathiolane-2R-carboxylate (CME) is a chiral phosphoramidite intermediate used in solid-phase oligonucleotide synthesis. Derived from cytidine and menthol, it facilitates high-efficiency coupling reactions. Molecular formula: C18H26N3O4S. CAS No.: Not publicly indexed in standard registries.
Requires anhydrous conditions during storage to prevent hydrolysis. Handle under inert atmosphere with appropriate PPE due to potential sensitization risks. Avoid direct skin contact and ensure proper ventilation.