Category:
Active Pharmaceutical Ingredients
CAS NO:
868851-47-2
Standard:
In-house Standards,
(1R,aR)-3-Diphenylphosphino-2-(4-diphenylphosphino-2,5-dimethyl-3-thienyl)-1,7,7-trimethylbicyclo[2.2.1]heptane is a specialized chiral diphosphine ligand derived from the bicyclic framework. Synthesized via cross-coupling of functionalized thienyl intermediates with diphenylphosphine derivatives under inert atmosphere, this compound features high enantiomeric purity essential for asymmetric catalysis.
Store under argon at -20°C to prevent oxidation. Handle in gloveboxes due to air sensitivity; wear PPE against phosphine exposure risks.