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Overview
2-Amino-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS: 100483-67-6) is a heterocyclic intermediate synthesized via cyclocondensation of malononitrile and urea derivatives. Its molecular formula is C5H4N4O, serving as a key scaffold for pyrimidine-based pharmaceuticals.
Application
- Pharmaceutical Synthesis: Precursor for antiviral agents and kinase inhibitors.
- Agrochemicals: Building block for herbicides targeting plant metabolic pathways.
- Material Science: Component in functional organic dyes and luminescent materials.
Precautions
- Store under inert atmosphere at temperatures below 25°C to prevent hydrolysis.
- Requires PPE handling due to potential skin irritation and inhalation risks.
- Not approved for direct clinical use; strictly limited to industrial manufacturing.