2-Amino-N - (2,2,2-trifluoroethyl) acetate hydrochloride CAS 1171331-39-7 can be used as a raw material for the synthesis of lotilana.
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Overview
2-Amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is a fluorinated amide intermediate used in pharmaceutical synthesis. The molecular formula is C4H8ClF3N2O and the CAS number is 100679-33-4. Core production involves amidation of trifluoroethylamine with chloroacetyl chloride followed by salt formation.
Application
- Synthesis of antiviral agents targeting RNA polymerases
- Building block for novel kinase inhibitor scaffolds
- Development of radiolabeled tracers for PET imaging
Precautions
Store under inert atmosphere at 2-8°C to prevent hydrolysis. Avoid inhalation of dust; use NIOSH-approved respirators. Not approved for direct clinical administration as an API.