Category:
Intermediates&Fine Chemicals
CAS NO:
2377605-91-7
Standard:
In-house Standards,
(2-chloro-5-methylpyridin-4-yl)boronic acid is a versatile heterocyclic boronic acid intermediate widely utilized in cross-coupling reactions. The core synthesis typically involves borylation of 2-chloro-5-methyl-4-bromopyridine or direct lithiation followed by trapping with trialkyl borate. Its molecular formula is C6H7BClNO2 and CAS number is 100980-35-4.
Store under inert atmosphere at low temperatures to prevent oxidation. Personnel must wear appropriate PPE including gloves and goggles due to potential skin irritation. Avoid contact with strong oxidizers and acids which may release hazardous gases.