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Overview
2-Cyclopropylaminonicotinic acid (CAS: 100589-64-2) is a specialized organic intermediate with molecular formula C9H10N2O2. It is primarily synthesized via nucleophilic substitution reactions involving nicotinic acid derivatives and cyclopropylamine under controlled thermal conditions.
Application
- Agricultural Chemistry: Serves as a critical scaffold for synthesizing novel neonicotinoid insecticides targeting pest resistance.
- Pharmaceutical R&D: Utilized in medicinal chemistry libraries to develop kinase inhibitors and CNS active agents.
Precautions
- Safety: Handle in a fume hood; avoid skin contact and inhalation of dust.
- Storage: Store in a cool, dry, ventilated area away from strong oxidizers and incompatible bases.