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Overview
2-Deoxy-2-fluoro-alpha-D-arabinofuranosyl bromide 3,5-dibenzoate is a specialized fluorinated nucleoside intermediate synthesized via selective bromination and benzoylation of protected sugar precursors. Its molecular formula is C21H18BrFO7.
Application
- Antiviral Drug Synthesis: Precursor for modified nucleosides targeting viral polymerase inhibition.
- Oncology Research: Building block for developing cytotoxic analogues in cancer therapy.
- Radiopharmaceuticals: Potential scaffold for fluorine-18 labeled diagnostic agents.
Precautions
Store under inert atmosphere at -20°C to prevent hydrolysis. Handle with PPE due to lachrymatory properties and potential mutagenicity. Strictly regulated for research use only; not approved for clinical administration.