CAS no. : 87199-14-2
Molecular weight: 151.95
PSA: 60.69000
Physical and chemical properties
Appearance and properties: gray - white crystal
Density: 1.25 g/cm3
Boiling point: 379.8 C at 760 mmHg
Flash: DHS 183.5 C
Refractive index: 1.566
2-Hydroxyphenylboronic acid (CAS 89466-08-0) is a versatile organoboron intermediate with molecular formula C6H7BO3. It is synthesized via lithiation of phenol followed by reaction with trialkyl borates or direct borylation methods, serving as a critical building block for Suzuki-Miyaura cross-coupling reactions in pharmaceutical and agrochemical manufacturing.
Store under inert atmosphere at 2-8°C to prevent oxidation. Handle in a fume hood wearing appropriate PPE due to potential respiratory sensitization. Not approved for direct clinical use; strictly an industrial raw material.