Category:
Active Pharmaceutical Ingredients
2-Ketoglutaric acid (CAS: 328-50-7), also known as alpha-ketoglutarate, is a pivotal five-carbon dicarboxylic acid serving as a central intermediate in the Krebs cycle. It is primarily synthesized via microbial fermentation or chemical oxidation of glutamic acid. The molecular formula is C5H6O5.
Storage requires sealed containers in cool, dry environments below 25°C. While generally safe for industrial use, high-dose clinical applications require strict medical supervision to avoid metabolic acidosis. Personal protective equipment is mandatory during handling to prevent skin irritation.