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Overview
2-(Trimethylsilyl)ethoxymethyl chloride (CAS 68197-45-9, C8H19ClOSi) is a specialized silylating reagent used in organic synthesis. It facilitates the protection of hydroxyl groups via the SEM ether moiety.
Application
- Pharmaceutical Manufacturing: Protecting intermediates during multi-step drug synthesis.
- Agrochemical Production: Synthesizing complex active ingredients for crop protection.
- Material Science: Fabrication of specialized silicon-based polymers.
Precautions
Strictly store under inert atmosphere at low temperatures to prevent hydrolysis. Requires full PPE due to corrosive and moisture-sensitive nature; not for direct clinical use.