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Overview
2,3,6-Trifluorophenylboronic acid is a specialized organoboron intermediate synthesized via halogen-metal exchange or lithiation followed by boric acid quenching. Its molecular formula is C6H5BF3O and CAS number is 104978-83-4.
Application
- Synthesis of fluorinated pharmaceuticals for kinase inhibitors.
- Production of advanced liquid crystal materials.
- Development of novel agrochemical fungicides.
Precautions
Store in a dry, inert atmosphere below 25°C to prevent hydrolysis. Handle with appropriate PPE due to potential respiratory irritation; not approved for direct clinical use as a drug substance.