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Overview
2,4-Dichloro-6,7-dimethoxyquinazoline (CAS: 15984-05-9) is a key heterocyclic intermediate synthesized via chlorination of dimethoxyquinazoline derivatives. Its molecular formula is C11H9Cl2N3O2. This compound serves as a critical scaffold in medicinal chemistry for constructing kinase inhibitors.
Application
- Pharmaceutical synthesis: Precursor for EGFR and VEGFR tyrosine kinase inhibitors.
- Agrochemicals: Intermediate for developing herbicidal agents targeting plant enzymes.
- Research tools: Used in biochemical assays to study protein-ligand interactions.
Precautions
Store in a cool, dry, ventilated area away from moisture. Handle with PPE due to potential skin irritation and respiratory hazards. Not intended for direct clinical use; strictly for industrial chemical synthesis only.