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Overview
2H-Tetrazole-2-acetic acid (CAS 100569-84-0) is a heterocyclic intermediate with molecular formula C3H4N4O2. It is synthesized via the cyclization of hydrazoic acid derivatives or nitroalkane rearrangement, serving as a key scaffold in medicinal chemistry.
Application
- Pharmaceutical synthesis: Precursor for angiotensin II receptor blockers and antiviral agents.
- Agrochemicals: Building block for novel herbicide formulations.
- Material science: Used in developing tetrazole-based metal-organic frameworks.
Precautions
Store under inert atmosphere at 2-8°C. Avoid contact with strong oxidizers due to explosive potential. Use PPE; inhalation may cause respiratory irritation. Not for direct human consumption.