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Overview
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol Mesylate is a specialized pharmaceutical intermediate featuring chiral diol and triazole moieties. Synthesized via asymmetric catalysis or resolution of racemic mixtures, it serves as a key building block for antifungal agents. Molecular formula: C12H13F2N3O5S; CAS No.: 98657-76-0.
Application
- Pharmaceutical Manufacturing: Precursor for developing broad-spectrum azole antifungals targeting fungal cytochrome P450 enzymes.
- Medicinal Chemistry: Used in SAR studies to optimize binding affinity and metabolic stability of novel drug candidates.
- API Production: Integrated into multi-step synthesis routes for active pharmaceutical ingredients in respiratory and systemic infections.
Precautions
Store in sealed containers under inert atmosphere at 2-8°C away from moisture. Handle with appropriate PPE due to potential skin irritation. Not for direct human consumption; strictly regulated for industrial R&D use only.