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Overview
3-Hydroxyphenylboronic acid is a key organoboron intermediate synthesized via lithiation of 3-hydroxybenzene followed by reaction with trialkyl borates. Molecular formula: C6H7BO3; CAS No: 12058-34-1.
Application
- Pharmaceutical synthesis as a scaffold for kinase inhibitors.
- Cross-coupling reactions (Suzuki-Miyaura) in agrochemical production.
- Material science for developing luminescent coordination polymers.
Precautions
- Store under inert atmosphere to prevent oxidation.
- Use appropriate PPE to avoid skin irritation and inhalation risks.
- Not approved for direct clinical use without further derivatization.