Category:
Chiral Intermediates
CAS NO:
179113-90-7
Standard:
In-house Standards,
;Chemical Purity0.97 ;Appearance:Off-white powder ;Molecular Formula: C7H6BF3O3
Molecular Weight:205.93
3-(Trifluoromethoxy)phenylboronic acid (CAS: 1261958-43-7, Formula: C7H6BF3O3) is a specialized organoboron intermediate synthesized via lithiation of 3-trifluoromethoxybenzene followed by quenching with trialkyl borates. It serves as a critical building block for cross-coupling reactions in pharmaceutical manufacturing.
Store under inert atmosphere at controlled temperatures below -20°C to prevent hydrolysis. Use appropriate PPE due to potential respiratory sensitization; avoid direct contact with skin or eyes during handling.