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Overview
(3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-β]furanyl Succinimidyl Carbonate is a specialized chiral coupling reagent derived from carbohydrate scaffolds. Synthesized via activated carbonate esterification, it features the molecular formula C14H17NO9 and CAS No. 850178-36-8.
Application
- Nucleoside Chemistry: Facilitates regioselective phosphorylation in antiviral drug synthesis.
- Glycoconjugation: Enables precise attachment of sugars to peptides for vaccine development.
- Pharmaceutical Intermediates: Serves as a key building block for complex heterocyclic compounds.
Precautions
- Storage: Maintain under inert atmosphere at -20°C to prevent hydrolysis.
- Safety: Handle with PPE; avoid contact due to potential sensitization risks.
- Regulatory: Restricted to R&D use only; not approved for direct clinical administration.