Category:
Chiral Intermediates
CAS NO:
147118-37-4
Standard:
In-house Standards,
Use: Intermediate of Rosuvastatin
Rosuvastatin Calcium is a potent HMG-CoA reductase inhibitor used for lipid management. The target structure contains an incorrect nomenclature; the actual active moiety is 4-(4-fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methylsulfonyl)amino]pyrimidin-5-yl-formyl derivative. Molecular Formula: C22H28FN3O6S. CAS No.: 133984-07-5 (Free Acid). Synthesis involves condensation of sulfonyl-pyrimidine intermediates.
Store at controlled room temperature (20-25°C) in dry, dark conditions. Avoid contact with skin and eyes due to potential irritation. Not suitable for patients with active liver disease or hypersensitivity to sulfonamides. Strict adherence to GMP guidelines is mandatory during handling.