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Overview
This compound, 4-chloro-7-hydroxy-6-methoxyquinoline-3-carbonitrile, is a specialized heterocyclic intermediate synthesized via Vilsmeier-Haack formylation followed by nucleophilic substitution. It serves as a critical scaffold for pharmaceutical development, with molecular formula C12H8ClNO3.
Application
- Pharmaceutical Synthesis: Precursor for quinoline-based kinase inhibitors and antimicrobial agents.
- Agrochemicals: Building block for novel fungicides targeting crop pathogens.
- Research: Standard reagent for medicinal chemistry optimization in drug discovery pipelines.
Precautions
Store in a cool, dry place away from oxidizers. Use appropriate PPE including gloves and goggles due to potential skin irritation. Not approved for direct human consumption or clinical use without further derivation.