Category:
Intermediates&Fine Chemicals
CAS NO:
3680-69-1
Standard:
In-house,
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS: 16980-25-1) is a key heterocyclic intermediate in pharmaceutical synthesis. Its molecular formula is C6H4ClN3. The core production process typically involves the chlorination of 7H-pyrrolo[2,3-d]pyrimidine using thionyl chloride or phosphorus oxychloride under controlled reflux conditions.
Store in a cool, dry, well-ventilated area away from incompatible oxidizers. Personnel must wear appropriate PPE including gloves and eye protection due to potential skin irritation. Avoid inhalation of dust; do not use in clinical settings without further purification.