4-Iodo-m-xylene is a reactant used in the preparation of paralog-selective Hsp90 inhibitors.Light Sensitive. Protect from light. Store away from oxidizing agents.
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Overview
4-Iodo-m-xylene (CAS: 1078-26-2) is a specialized iodinated aromatic intermediate used in pharmaceutical synthesis and materials science. Produced via electrophilic iodination of m-xylene, its molecular formula is C8H9I.
Application
- Pharmaceuticals: Key building block for radiopharmaceuticals and kinase inhibitors.
- Organic Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
- Materials Science: Precursor for functionalizing polymers with iodine moieties.
Precautions
Store in a cool, dry, well-ventilated area away from light. Use appropriate PPE including gloves and goggles due to potential skin irritation and environmental toxicity. Avoid inhalation of dust or vapors during handling.