Category:
Advanced Intermediates
CAS NO:
5720-05-8
Standard:
ChP,USP,EP,
Product Name: 4-methylphenylboronic acid
CAS: 5720-05-8
4-Tolylboronic acid (CAS 10529-70-1, C7H9BO2) is a specialized organoboron intermediate synthesized via halogen-metal exchange or direct borylation of p-xylene derivatives. It serves as a critical coupling partner in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures.
Store in sealed containers under inert atmosphere at controlled temperatures to prevent oxidation. Personnel must utilize appropriate PPE including respiratory protection and chemical-resistant gloves due to potential respiratory sensitization and skin irritation hazards.