Lumateperone Intermediate
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Overview
(4aS,9bR)-Ethyl 6-bromo-5-(2-(methylamino)-2-oxoethyl)-3,4,4a,5-tetrahydro-1 H-pyrido[4,3-b]indole is a chiral pharmaceutical intermediate synthesized via asymmetric catalytic hydrogenation. Molecular formula: C18H20BrN3O2.
Application
- Pharmaceutical synthesis for novel indole-based kinase inhibitors.
- Research on stereoselective drug delivery systems.
- Development of anti-inflammatory therapeutic agents.
Precautions
Requires storage below -20°C under inert atmosphere. Strict PPE compliance mandatory during handling due to potential mutagenicity and environmental toxicity.