Category:
Other Specialized Reagents
CAS NO:
465515-31-5
Standard:
Chp,
5-Carboxythiophene-2-boronic acid (CAS: 1008764-69-9) is a heterocyclic boronic acid derivative featuring a thiophene ring substituted with carboxyl and boronic acid groups. Its molecular formula is C6H5BNO4S. This compound is primarily synthesized via lithiation of 5-carboxythiophene followed by reaction with trialkyl borates, serving as a critical building block for Suzuki-Miyaura cross-coupling reactions in pharmaceutical R&D.
Store under inert atmosphere at 2-8°C to prevent oxidation. Avoid direct contact with skin and eyes; wear appropriate PPE including gloves and goggles during handling due to potential irritant properties.