Category:
Chiral Intermediates
CAS NO:
51-21-8
Standard:
In-house Standards,
/
5-Fluorouracil (CAS: 51-21-8) is a pyrimidine analog antineoplastic agent synthesized via fluorination of uracil derivatives. Its molecular formula is C5H4FN2O2. This compound acts as an antimetabolite, inhibiting thymidylate synthase to disrupt DNA synthesis.
Requires strict handling protocols due to teratogenicity and mutagenicity. Store in a cool, dry place below 25°C away from light. Clinical use mandates monitoring for myelosuppression and gastrointestinal toxicity.