Category:
Chiral Intermediates
CAS NO:
496946-78-2
Standard:
In-house Standards,
HPLC>98%
5-(Trifluoromethyl)-1H-indole-2-carboxylic acid (CAS: 136789-43-6) is a fluorinated indole scaffold widely utilized in pharmaceutical synthesis. Its core production involves the Vilsmeier-Haack formylation of 5-trifluoromethylindole followed by oxidation.
Store under inert atmosphere at -20°C to prevent hydrolysis. Personnel must wear chemical-resistant PPE due to potential skin irritation and corrosive properties during handling.