Parent nucleus of Cefteram
Chemical name:7-amino-3-(5-methyl tetrazole) methyl-4-cephalosporanic acid,(6R,7R)-7-Amino-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.82549-51-7
Molecular formula:C10H12N6O3
Molecular weight:296.07
Properties:White or light yellow crystalline powder
Use:Intermediate of cefteram pivoxil
(6R,7R)-7-Amino-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a specialized beta-lactam intermediate featuring a fused bicyclic core with a tetrazole side chain. Its synthesis typically involves the condensation of specific cephalosporin precursors under strict stereochemical control to ensure the retention of the (6R,7R) configuration.
Store in a cool, dry place under inert atmosphere to prevent hydrolysis of the beta-lactam ring. Personnel must wear appropriate PPE due to potential sensitization risks associated with beta-lactam structures. Do not use without validated purity certificates for clinical applications.