7-Ethyl-10-hydroxycamptothecin/ CAS#86639-52-3/ 7-乙基-10-羟基喜树碱
(SN-38)/ Manufacturer/ ISO cer./ Irinotecan intermediate
7-Ethyl-10-hydroxycamptothecin (SN-38), CAS# 86639-52-3, is the active metabolite of irinotecan. It functions as a potent topoisomerase I inhibitor with significantly higher cytotoxicity than its parent compound. The molecular formula is C22H20N4O6. Production typically involves semi-synthetic conversion from camptothecin derivatives under strict ISO certified manufacturing protocols.
Strictly handle in controlled environments due to high potency and potential genotoxicity. Store at -20°C in dark, dry conditions away from incompatible oxidizers. Clinical use requires specialized medical supervision to manage severe adverse effects like neutropenia and diarrhea.