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Overview
Abacavir Hydrochloride is a synthetic nucleoside analogue reverse transcriptase inhibitor (NRTI) produced via chiral synthesis. It serves as the active pharmaceutical ingredient (API) for treating HIV-1 infection. Molecular Formula: C14H22N6O·HCl; CAS No.: 136470-78-5.
Application
- Pharmaceutical Manufacturing: Core component in fixed-dose combination tablets for antiretroviral therapy.
- Clinical Treatment: Integrated into regimens to suppress viral replication in HIV-positive patients.
- Research & Development: Utilized in virology studies for novel drug formulation and efficacy testing.
Precautions
Strict screening for HLA-B*5701 allele is mandatory prior to prescription to prevent hypersensitivity reactions. Store in sealed containers at controlled room temperature, protected from moisture and light.