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Overview
Abaloparatide is a synthetic analog of human parathyroid hormone-related protein (PTHrP). Its molecular formula is C126H195N37O38S and CAS number is 409573-50-2. Produced via solid-phase peptide synthesis, it functions as a bone anabolic agent.
Application
- Treatment of postmenopausal osteoporosis to reduce fracture risk.
- Management of severe osteoporosis in patients at high risk for fractures.
- Research into bone regeneration therapies within pharmaceutical R&D.
Precautions
Contraindicated in patients with increased baseline risk for osteosarcoma. Must be stored under refrigeration at 2°C to 8°C. Strictly limit duration of therapy to one year due to safety concerns observed in animal studies.