Category:
Active Pharmaceutical Ingredients
CAS NO:
/
Standard:
In-house Standards,
1,Product Name :ADC drug(Maytansinoids,Exatecans,MMAE/MMAFs)
2,Standard :In-house Standards
3,Grade :pharmaceutical grade
4,Factory Location :Suzhou Industrial Park, China
Antibody-Drug Conjugates (ADCs) utilize potent cytotoxic payloads like Maytansinoids, Exatecans, and MMAE/MMAF linked to monoclonal antibodies. These highly specific agents deliver toxins directly to tumor cells, minimizing systemic exposure. Key linkers include disulfide bonds for MMAE and cleavable peptide linkers for stability.
Strictly handle as hazardous cytotoxins requiring PPE and containment. Store payloads at -20°C in desiccated conditions. Clinical use mandates monitoring for neutropenia and neuropathy due to off-target toxicity risks.