Category:
Chiral Intermediates
CAS NO:
142340-99-6
Standard:
In-house Standards,
-
Adefovir Dipivoxil is a prodrug of adefovir, an acyclic nucleotide phosphonate analog. It serves as the active moiety for treating chronic hepatitis B virus infections. The compound is synthesized via esterification to enhance oral bioavailability.
Contraindicated in patients with severe renal impairment without dose adjustment. Must be stored in a cool, dry place below 25°C protected from light. Strict adherence to clinical dosing guidelines is required to prevent nephrotoxicity.