Category:
Intermediates&Fine Chemicals
CAS NO:
848133-35-7
Standard:
In-house Standards,
Afatinib Intermediate (CAS 848133-35-7) is a key synthetic precursor for the kinase inhibitor Afatinib. It features an optimized chloroquinazoline core structure essential for high-yield coupling reactions. The molecular formula is C20H19ClN6O, ensuring precise stereochemistry for pharmaceutical manufacturing.
Store under inert atmosphere at 2-8°C to prevent hydrolysis. Handle with appropriate PPE due to potential skin irritation; avoid inhalation of dust. Not intended for direct clinical administration without further processing.