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Overview
ALISERTIB is a potent, selective Aurora kinase A (AURKA) inhibitor developed for oncology research. Its core mechanism involves disrupting mitotic spindle assembly to induce cell cycle arrest. Molecular Formula: C24H25N7O2; CAS No.: 1206856-95-0.
Application
- Oncology: Investigating efficacy in solid tumors and hematological malignancies.
- Drug Discovery: Serving as a reference standard for AURKA pathway studies.
- Biomarker Analysis: Validating Aurora kinase activity in preclinical models.
Precautions
Strictly for laboratory research use only; not approved for clinical therapy. Store under inert atmosphere at -20°C. Handle with appropriate PPE due to potential cytotoxicity and reproductive hazards.