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*The following content is generated by AI and is for reference only.
Overview
Alogliptin Benzoate is a pharmaceutical intermediate, specifically the benzoate salt form of Alogliptin. It serves as a potent and selective inhibitor of dipeptidyl peptidase-4 (DPP-4), crucial for type 2 diabetes management. The synthesis typically involves coupling alogliptin with benzoic acid under controlled conditions to enhance stability.
Molecular Formula: C
18H
22FN
5O·C
7H
6O
2
CAS Number: 907659-54-9
Application
- Pharmaceutical Manufacturing: Primary raw material for producing branded DPP-4 inhibitors like Nesina.
- Research & Development: Used in clinical trials to evaluate metabolic efficacy and pharmacokinetics.
- Quality Control: Standard reference substance for purity analysis in API production lines.
Precautions
- Storage: Maintain at 2-8°C in sealed, moisture-proof containers away from direct light.
- Safety: Handle with PPE; avoid inhalation or skin contact due to potential irritancy.
- Regulatory: Not for human consumption directly; strictly regulated as an active pharmaceutical ingredient.