Category:
Active Pharmaceutical Ingredients
CAS NO:
20537-88-6
Standard:
In-house Standards,
Amifostine is a cytoprotective agent primarily used to reduce renal toxicity from cisplatin. It acts as a prodrug converted by alkaline phosphatase into its active thiol metabolite, which scavenges free radicals. The compound features the molecular formula C8H19O4P2S and CAS No. 87068-57-5.
Strict clinical monitoring is required due to risks of severe hypotension. Storage must be maintained at controlled room temperature with protection from light. Use is contraindicated in patients with significant cardiovascular compromise or those allergic to aminothiols.