Category:
Intermediates&Fine Chemicals
CAS NO:
88150-62-3
Standard:
ChP,
Amlodipine intermediates are key synthetic building blocks for the production of amlodipine besylate, a widely used calcium channel blocker. The primary synthesis route involves condensation of 2-(2-aminoethyl)-6-methyl-3,5-pyridinedicarboxylic acid derivatives with ethyl 4-chloro-3-nitrobenzoate. Typical specifications include molecular formula C18H20ClN3O4 and CAS number 79507-52-3.
Storage requires sealed containers under inert atmosphere at temperatures below 25°C. Personnel must wear appropriate PPE due to potential irritant properties. Regulatory compliance with GMP guidelines is mandatory for all pharmaceutical grade batches.