Apixaban is a pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases. It has a role as an anticoagulant and an EC 3.4.21.6 (coagulation factor Xa) inhibitor. It is a pyrazolopyridine, a member of piperidones, a lactam and an aromatic ether.
Apixaban is a direct Factor Xa inhibitor used as an anticoagulant. Synthesized via multi-step organic processes, its molecular formula is C20H19ClN4O5 (CAS: 639849-41-7).
Contraindicated in patients with active bleeding or severe hepatic impairment. Store in controlled environments below 25°C to maintain stability. Strict adherence to dosing protocols is required to minimize hemorrhage risks.