Apixaban is a factor Xa inhibitor anticoagulant indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
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Overview
Apixaban is a potent, selective oral Factor Xa inhibitor used as an anticoagulant. Its core synthesis involves multi-step organic reactions yielding the molecular formula C₂₀H₁₈BrN₅O (CAS: 603471-88-9).
Application
- Pharmaceutical Manufacturing: Active Pharmaceutical Ingredient (API) for preventing stroke in non-valvular atrial fibrillation.
- Vascular Care: Treatment of deep vein thrombosis and pulmonary embolism following orthopedic surgeries.
- R&D Sector: Reference standard for analytical method validation in quality control laboratories.
Precautions
Strictly contraindicated in patients with active pathological bleeding. Store API in a cool, dry place below 25°C under inert atmosphere to maintain chemical stability and prevent hydrolysis.