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Overview
Avanafil is a potent PDE5 inhibitor developed for treating erectile dysfunction. Its chemical structure features a distinct pyrazolopyrimidine scaffold, with molecular formula C26H31N7O4S and CAS No. 202298-27-7. Core synthesis involves condensation reactions of specific heterocyclic precursors.
Application
- Pharmaceutical Manufacturing: Active pharmaceutical ingredient (API) production for oral tablets targeting male sexual health.
- Research & Development: Clinical trials investigating vasodilation mechanisms and cardiovascular interactions.
Precautions
Strictly contraindicated with nitrates due to hypotension risks. Store in cool, dry environments below 25°C away from direct sunlight. Handle with PPE to avoid dermal absorption during processing.