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Overview
Balsalazide Disodium Dihydrate is an active pharmaceutical ingredient (API) defined as a prodrug of mesalamine, synthesized via diazotization and coupling reactions. Its molecular formula is C21H16N4Na2O8·2H2O with CAS No. 91607-56-0.
Application
- Inflammatory Bowel Disease (IBD): Primary treatment for mild-to-moderate ulcerative colitis.
- Gastroenterology: Targeted delivery of 5-ASA to the colon for mucosal healing.
- Pharmaceutical Manufacturing: Raw material for oral tablet formulations in global markets.
Precautions
Contraindicated in patients with hypersensitivity to salicylates or sulfasalazine. Store in tightly closed containers at controlled room temperature (15-25°C) away from moisture to prevent hydrolysis.