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Beta Cyclodextrin Cas 7585-39-9 Zhiyuan Β-cyclodextrin
Beta Cyclodextrin Cas 7585-39-9 Zhiyuan Β-cyclodextrin

Beta Cyclodextrin Cas 7585-39-9 Zhiyuan Β-cyclodextrin

Category:
Other Excipients
CAS NO:
7585-39-9
Standard:
ChP,USP,EP,
Price Range:
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Main Sales Markets:
North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
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Basic Info

CAS Number
7585-39-9
Pharmacopoeia
ChP,USP,EP
Grade
Food Grade
Is Manufacturer
No
Packaging & Delivery
Packaging Specification
20kg/carton
Minimum Order Quantity
1kg

Product Description

Basic information of beta cyclodextrin

Alias: beta cyclodextrin, cycloheptase, cyclomaltose

..........................................................................................................

Abbreviation: BCD

..........................................................................................................

CAS NO. :7585-39-9

..........................................................................................................

Molecular formula: C42H70O35

 

 

PROPERTY

SPECIFICATION

Appearance

White, practically odorless, fine crystalline powder having a 

slightly sweet taste. Sparingly soluble in water

Identification

IR

Same absorption bands as USP Beta Cyclodextrin RS

 

LC

The retention time of the major peak of sample solution

corresponds to the standard solution.

 

Optical rotation

+160°~+164°

 

Iodine test solution

A yellow-brown precipitate is formed

Residue on Ignition

≤ 0.1%

Reducing Sugars

≤ 0.2%

Light-absorbing impurities

Between 230nm and 350nm,the absorbance is not greater 

than 0.10; and between 350nm and 750nm, the

absorbance is not greater than 0.05.

Alpha cyclodextrin

≤0.25%

Gamma cyclodextrin

≤0.25%

Other related substances

≤0.5%

Water determination

≤14.0%

Color and Clarity of  Solution

0.2g/20ml solution is clear and Colorless

pH

5.0~8.0

Assay

98.0%°~102.0%

The total aerobic microbial count

≤1000cfu/g

The total combined moulds and yeasts count

≤100cfu/g

 

Properties of beta cyclodextrin:

Betacyclodextrin is white crystal, which is easy to crystallize in water. The solubility in water is relatively low, which is 1.85% at room temperature. The solubility increases with the increase of temperature. It is not hygroscopic, but easy to form stable hydrate. The degree of hydration between 50-70% relative humidity is equivalent to the absorption of 10-11 water molecules per molecule of β - CD (moisture content is 13.7-14.8%). The isotherm curve of moisture absorption is two phases. It is insoluble in general organic solvents, but slightly soluble in pyridine, dimethylformamide, dimethyl sulfoxide and ethylene glycol.

The role of beta cyclodextrin in the field of Medicine:

As a new pharmaceutical excipient, β - cyclodextrin is mainly used to enhance the stability of drugs, prevent the oxidation and decomposition of drugs, improve the dissolution and bioavailability of drugs, reduce the toxic and side effects of drugs, and cover up the peculiar smell and odor of drugs. In food manufacturing, it is mainly used to eliminate odor, improve the stability of spices, flavors and pigments, enhance the emulsifying capacity and moisture resistance. To improve the taste of food, it is a good stabilizer, emulsifier and flavor corrector in the pharmaceutical, food and chemical industry.

The role of beta cyclodextrin in the field of food:

Cyclodextrin has the function of protecting some substances from oxidation, light, heat, volatilization and solid phase, so it can be used as a multifunctional food additive. Its main uses are as follows:

1. In the process of food processing and preservation, β - CD can prevent the volatilization of various spices, oils, spices and other volatile substances, and keep the food flavor unchanged for a long time. β - CD can keep the stability of pigments, amino acids and vitamins which are easy to oxidize, decompose in light and deteriorate in heat.

2. β - CD can remove the fishy smell of fish and meat, the unpleasant taste of foods supplemented with vitamin B and the peculiar smell of other foods, increase the palatability of foods, and improve the taste of sweeteners such as saccharin and sodium cyclamate.

3. β - CD can make the beverage with high oil content, such as ice cream, coffee beverage and other emulsified food, form long-term stable emulsion. If it is used with food emulsifier, the emulsifying effect is better.

4. β - CD can release food preservatives and preservatives slowly, improve the antiseptic effect and prolong the shelf life of food.

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