Category:
Other Specialized Reagents
Standard:
In-house Standards,
Beta-D-homoDNA-G(iBu) Phosphoramidite is a specialized synthetic nucleoside building block designed for automated solid-phase oligonucleotide synthesis. It features an isobutyryl-protected guanosine moiety with a homo-DNA backbone modification to enhance nuclease stability and binding affinity. The compound typically follows the molecular formula C24H38N5O7P (CAS: 196506-44-8), synthesized via standard phosphoramidite coupling chemistry.
This reagent must be stored under inert atmosphere at -20°C to prevent hydrolysis. Strict adherence to PPE protocols is required due to potential sensitization and toxicity. Not intended for direct clinical administration; usage is restricted to research-grade manufacturing environments.