BIBW2992 DiMaleate
CAS NO:850140-73-7
MF:C24H25ClFN5O3
BIBW2992 DiMaleate;BIBW2992-MA2;Afatinib (diMaleate);Afatinib (diMaleate), BIBW2992;2-ButenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(diMethylaMino)-, (2E)-, (2Z)-2-butenedioate (1:2);(2E)-N-(4-[(3-chloro-4-fluorophenyl)aMino]-7-{[(3S);Afatinib double Maleate;Afatinib (BIBW2992) Dimaleate
BIBW2992 DiMaleate is the maleate salt of a potent, irreversible EGFR/HER2 tyrosine kinase inhibitor. Molecular Formula: C25H27N7O4; CAS No.: 100682-65-7. Synthesized via reaction of BIBW2992 with maleic acid to enhance solubility for pharmaceutical formulation.
Restricted to clinical trials under strict regulatory approval; requires storage in cool, dry conditions below -20°C. Handle with PPE due to potential cytotoxicity and mutagenic risks during synthesis.