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Overview
Bivalirudin Trifluoroacetate is a synthetic direct thrombin inhibitor, typically supplied as a TFA salt for enhanced solubility. Its core synthesis involves solid-phase peptide synthesis followed by purification. Molecular Formula: C46H70N14O12S2·nCF3COOH; CAS No.: 195382-12-2.
Application
- Pharmaceutical R&D: Used in assay development and stability testing of anticoagulant drugs.
- Cardiovascular Research: Serves as a reference standard for studying acute coronary syndromes.
- Quality Control: Employed as an internal standard in HPLC analysis for drug purity verification.
Precautions
- Storage: Must be stored at -20°C under inert atmosphere to prevent hydrolysis.
- Safety: Handle with gloves in a fume hood due to potential sensitization risks.
- Usage: Intended for research use only; not approved for human clinical administration in this form.